Browsing Facultad de Ciencias Médicas by Language "eng"
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Effects of ω-3 PUFA-enriched diet on growth parameters in a syngenic murine model of breast adenocarcinoma: a possible role for estrogen receptor alpha
(2013)Background: Breast cancer (BC) is the most common tumour among women and 75% of BC are estrogen receptor (ER)dependent. In particular, ERα promotes tumour growth, while ERβ has an anti-proliferative effect [1]. Epidemiological ... -
Enteric viruses in surface waters from Argentina: molecular and viable-virus detection
(2018)Water resources contaminated with wastewater are an important source for the dissemination of enteric viruses with an impact on the health of the population. The aim of the study was to assess the viral contamination of ... -
Genetic defects in the liver phosphorylase system in Argentine patients nosological definition through a strategy of enzimatic and molecular analysis
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas., 2013)The phosphorylase and phosphorylase-b kinase (PHK) deficiencies in the liver constitute the phosphorylase system defects (PSD), leading to Glycogenosis Type VI (GSD-VI) and Type IX (GSD-IX), respectively. The hepatic ... -
High concentrations of sodium chloride improve microbicidal activity of ibuprofen against common cystic fibrosis pathogens
(Multidisciplinary Digital Publishing Institute, 2018)Ibuprofen (IBU-H), a widely used anti-inflammatory, also shows a marked antimicrobial effect against several bacterial species, including those involved in cystic fibrosis such as Pseudomona aeruginosa, methicillin resistant ... -
Human Papillomavirus: analisis of knowledge among general population
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas., 2013)La mayoría de los estudios de VPH, se orientan a la etiología y la historia de la infección, sin embargo, pocos trabajos evalúan el conocimiento de la población. Objetivo: analizar el conocimiento poblacional, sobre el ... -
Identification of dietary patterns in urban population of Argentina: study on diet-obesity relation in population-based prevalence study
(2016-04)BACKGROUND/OBJECTIVES: In Argentina, obesity prevalence rose from 14.6% in 2005 to 20.8% in 2013. Although the number of studies on noncommunicable diseases and dietary patterns as a unique dietary exposure measure has ... -
Implications of oxidative stress and placental structural alterations in Trypanosoma cruzi infection in vitro and ex vivo
(V Latin American Symposium on Maternal Fetal Interaction & Placenta, 2013)Human placenta participates in the control of Chagas congenital infection, which could be due by nitric oxide synthase (NOS) and peroxinitrites which are deleterious for Trypanosoma cruzi and placental tissue. We proposed ... -
In vitro modifications on functional activity of mice sperm induced by the addition of ghrelin
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas, 2013)Ghrelin (Ghr) is a peptide that modulates reproductive physiology, linking reproduction with energy balance. The expression of the peptide and its receptor has been reported in testis, prostate and sperm; the presence of ... -
Inefficient N2-like neutrophils are promoted by androgens during infection
(2018)Neutrophils are major effectors of acute inflammation against infection and tissue damage, with ability to adapt their phenotype according to the microenvironment. Although sex hormones regulate adaptive immune cells, which ... -
Inhibitory effect of n3 polyunsaturated fatty acids on cancer cell growth by p53 activation
(Argentine Society for biochemistry and molecular biology research, 2013)Different evidences show the regulatory effect of n-3 and n-6 polyunsaturated fatty acids (PUFAs) on carcinogenesis, however how PUFAS modulate tumor development remains unknown. In this report, we analyzed the in vitro ... -
Inhibitory receptor expression on T cells as marker of disease activity and target to regulate effector cellular responses in Rheumatoid Arthritis
(2018)Objective: Inhibitory receptors are essential for the regulation of effector immune responses and may play critical roles in autoimmune diseases. We evaluated whether inhibitory receptor expression on T cells from patients ... -
Intrahipotalamic ghrelin administration decreases sperm concentration and motility in mice
(Universidad Nacional de Córdoba, 2013)Ghrelin (Ghr) is a peptide secreted primarily in the stomach and hypothalamus. However, Ghr and its receptors are synthesized also in many tissues of the reproductive tract. In situations of hiperghrelinemia (fasting or ... -
Involment of 5HT1A receptors in the angiogenic-like effects of the Uncaria tomentosa (Willd) DC aqueous extract
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2013)The aqueous extract of Uncaria tomentosa (EUT) prepared by decoction of the root and stem bark is used in the treatment of several diseases. There is evidence showing the interaction of the extract components with serotonin ... -
Long-term relationship between tobacco use and weight loss after sleeve gastrectomy
(2018)BACKGROUND: Smoking cessation had been typically associated with weight gain. We have reported that there is no relationship between tobacco use and weight loss after bariatric surgery in the short term. The objective of ... -
Neuronal ceroid lipofuscinosis type cln2: prevalent phenotypes and genotypes in Latin America
(2013)The Neuronal Ceroid Lipofuscinoses (NCLs), inherited neurodegenerative disorders, are the second most frequent group lysosomal pathologies (LP) of childhood. They are characterized by the pathological accumulation of ... -
Neuronal degeneration in mice induced by an epidemic strain of Saint Louis Encephalitis virus isolated in Argentina
(2018)Saint Louis encephalitis virus (SLEV) is a neglected flavivirus that causes severe neurological disorders. The epidemic strain of SLEV, CbaAr-4005, isolated during an outbreak in Córdoba city (Argentina), causes meningitis ... -
NLRP3 inflammasome and caspase-1/11 pathway orchestrate different outcomes in the host protection against trypanosoma cruzi acute infection
(2018)Infection with protozoan parasite Trypanosoma cruzi results in activation of nucleotide-binding domain and leucine-rich repeat containing receptors (NLRs). NLR activation leads to inflammasome formation, the activation of ... -
Nonsense mediated mRNA decay affects nonsense transcripts levelsand in vitro response to gentamicin and ataluren in X-ALD
(2013)Background: X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ABCD1 gene, characterized by increased concentrations of very long-chain fatty acids due to a defect in peroxisomal β-oxidation. ... -
Nutritional profile and obesity: results from a random‑sample population‑based study in Córdoba, Argentina
(2015-03-31)Introduction Obesity is a chronic, heterogeneous, multifactorial disease, which has sharply increased in prevalence in both developed and developing countries. This study aimed to estimate the prevalence of obesity and to ... -
Ornithine transcarbamylase deficiency: identification of mutations, computational validation, and phenotypic correlation in argentinian patients
(2013)Ornithine transcarbamylase deficiency (OTCD; Online Mendelian Inheritance in Man [OMIM] 311250) is an urea cycle defect with Xlinked inheritance. In hemizygous males, neonatal or late onset depends on the degree of ...