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Effects of ω-3 PUFA-enriched diet on growth parameters in a syngenic murine model of breast adenocarcinoma: a possible role for estrogen receptor alpha
(2013)
Background: Breast cancer (BC) is the most common tumour among women and 75% of BC are estrogen receptor
(ER)dependent. In particular, ERα promotes tumour growth, while ERβ has an anti-proliferative effect [1].
Epidemiological ...
Downregulation of GLI1- dependent survival pathway underlies arachidonic acid antitumoral activity
(Argentine Society for biochemistry and molecular biology research, 2013)
Numerous studies have demonstrated a role for essential fatty acids (ePUFAs) during tumor evelopment. However, the molecularmechanism underlying this phenomenon remains elusive. Here, we defined a novel molecular mechanism ...
Inhibitory effect of n3 polyunsaturated fatty acids on cancer cell growth by p53 activation
(Argentine Society for biochemistry and molecular biology research, 2013)
Different evidences show the regulatory effect of n-3 and n-6 polyunsaturated fatty acids (PUFAs) on carcinogenesis, however how PUFAS modulate tumor development remains unknown. In this report, we analyzed the in vitro ...