Now showing items 1-2 of 2

    • Downregulation of GLI1- dependent survival pathway underlies arachidonic acid antitumoral activity 

      Comba, Andrea; Pasqualini, María Eugenia; Vara Mesler, Mariana; Silva, Renata Alejandra; García Fernandez Barrera, M; Fernández Zapico, Martín; Eynard, Aldo (Argentine Society for biochemistry and molecular biology research, 2013)
      Numerous studies have demonstrated a role for essential fatty acids (ePUFAs) during tumor evelopment. However, the molecularmechanism underlying this phenomenon remains elusive. Here, we defined a novel molecular mechanism ...
    • Inhibitory effect of n3 polyunsaturated fatty acids on cancer cell growth by p53 activation 

      Garay, María Isabel; Comba, Andrea; Vara Mesler, Marianela; Silva, Renata Alejandra; Quiroga, Patricia; Pasqualini, María Eugenia (Argentine Society for biochemistry and molecular biology research, 2013)
      Different evidences show the regulatory effect of n-3 and n-6 polyunsaturated fatty acids (PUFAs) on carcinogenesis, however how PUFAS modulate tumor development remains unknown. In this report, we analyzed the in vitro ...