Browsing FCM - Congresos 2013 by Author "Pasqualini, María Eugenia"
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Downregulation of GLI1- dependent survival pathway underlies arachidonic acid antitumoral activity
Comba, Andrea; Pasqualini, María Eugenia; Vara Mesler, Mariana; Silva, Renata Alejandra; García Fernandez Barrera, M; Fernández Zapico, Martín; Eynard, Aldo (Argentine Society for biochemistry and molecular biology research, 2013)Numerous studies have demonstrated a role for essential fatty acids (ePUFAs) during tumor evelopment. However, the molecularmechanism underlying this phenomenon remains elusive. Here, we defined a novel molecular mechanism ... -
Effects of ω-3 PUFA-enriched diet on growth parameters in a syngenic murine model of breast adenocarcinoma: a possible role for estrogen receptor alpha
Vara Messler, Marianela; Pasqualini, María Eugenia; Comba, Andrea; Toniolo, Alicia; Trenti, Annalisa; Quiroga, Patricia; Valentich, Mirta Ana; Bolego, Chiara (2013)Background: Breast cancer (BC) is the most common tumour among women and 75% of BC are estrogen receptor (ER)dependent. In particular, ERα promotes tumour growth, while ERβ has an anti-proliferative effect [1]. Epidemiological ... -
Inhibitory effect of n3 polyunsaturated fatty acids on cancer cell growth by p53 activation
Garay, María Isabel; Comba, Andrea; Vara Mesler, Marianela; Silva, Renata Alejandra; Quiroga, Patricia; Pasqualini, María Eugenia (Argentine Society for biochemistry and molecular biology research, 2013)Different evidences show the regulatory effect of n-3 and n-6 polyunsaturated fatty acids (PUFAs) on carcinogenesis, however how PUFAS modulate tumor development remains unknown. In this report, we analyzed the in vitro ...