Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and Torrontés Wine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation
Date
2024-06-07Author
Tapia, Pablo Ezequiel
Silva, Ana Margarida
Delerue Matos, Cristina
Moreira, Manuela
Rodrigues, Francisca
Torres Carro, Romina
Santi, María Daniela
Ortega, María Gabriela
Blázquez, María Amparo
Arena, Mario Eduardo
Alberto, María Rosa
ORCID
https://orcid.org/0000-0002-1823-9816https://orcid.org/0000-0002-3924-776X
https://orcid.org/0000-0003-1500-9211
https://orcid.org/0000-0001-8803-0041
https://orcid.org/0000-0002-3866-1424
https://orcid.org/0000-0002-2400-9099
https://orcid.org/0000-0002-2400-9099
https://orcid.org/0000-0003-1984-5233
https://orcid.org/0000-0002-4173-9499
Metadata
Show full item recordAbstract
Hydroalcoholic extracts from Malbec and Torrontés wine pomaces (Vitis vinifera L.) originating
from the high-altitude vineyards of Argentina’s Calchaquí Valleys were characterized. Total
phenolics, hydroxycinnamic acids, orthodiphenols, anthocyanins, non-flavonoid phenolics, total
flavonoids, flavones/flavonols, flavanones/dihydroflavonols, and tannins were quantified through
spectrophotometric methods, with the Malbec extract exhibiting higher concentrations in most of
phytochemical groups when compared to Torrontés. HPLC-DAD identified more than 30 phenolic
compounds in both extracts. Malbec displayed superior antiradical activity (ABTS cation, nitric oxide,
and superoxide anion radicals), reduction power (iron, copper, and phosphomolybdenum), hypochlorite
scavenging, and iron chelating ability compared to Torrontés. The cytotoxicity assessments
revealed that Torrontés affected the viability of HT29-MTX and Caco-2 colon cancer cells by 70% and
50%, respectively, at the highest tested concentration (1 mg/mL). At the same time, both extracts
did not demonstrate acute toxicity in Artemia salina or in red blood cell assays at 500 μg/mL. Both
extracts inhibited the lipoxygenase enzyme (IC50: 154.7 and 784.7 μg/mL for Malbec and Torrontés),
with Malbec also reducing the tyrosinase activity (IC50: 89.9 μg/mL), and neither inhibited the
xanthine oxidase. The substantial phenolic content and diverse biological activities in the Calchaquí
Valleys’ pomaces underline their potentialities to be valorized for pharmaceutical, cosmetic, and
food industries.
xmlui.dri2xhtml.METS-1.0.item-citation
Tapia, P.E.; Silva, A.M.; Delerue-Matos, C.; Moreira, M.; Rodrigues, F.; Torres Carro, R.; Santi, M.D.; Ortega, M.G.; Blázquez, M.A.; Arena, M.E.; et al. Exploring the Phytochemical Composition and the Bioactive Properties of Malbec and TorrontésWine Pomaces from the Calchaquíes Valleys (Argentina) for Their Sustainable Exploitation. Foods 2024, 13, 1795. https://doi.org/10.3390/foods13121795
Other links
https://www.mdpi.com/2304-8158/13/12/1795Collections
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