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dc.contributor.authorStroppa, María Mercedes
dc.contributor.authorGiménez, Ignacio
dc.contributor.authorGarcía, Beatriz A.
dc.date.accessioned2023-12-05T21:24:57Z
dc.date.available2023-12-05T21:24:57Z
dc.date.issued2018
dc.identifier.issn0002-9637
dc.identifier.urihttp://hdl.handle.net/11086/550116
dc.description7 p.es
dc.description.abstractTo contribute to a better understanding of the molecular bases of the circadian biological rhythms in Chagas disease vectors, in this work we identified functional domains in the sequences of the clock protein PERIOD in Rhodnius prolixus and Triatoma infestans and analyzed the expression of the period gene at mRNA level in T. infestans. The PERIOD protein sequences comparison among these species and those from other insects revealed that the most similar regions are the PAS domains and the most variable is the COOH-terminal. On the other hand, the per gene expression in nervous tissue of adults T. infestans varies with a daily canonical rhythm in groups of individuals maintained under photoperiod (LD) and constant dark (DD), showing a significant peak of expression at sunset. The pattern of expression detected in LD persists under the DD condition. As expected, in the group maintained in constant light (LL), no daily increase was detected in per transcript level. Besides, the presence of per transcript in different tissues of adult individuals and in nervous tissue of nymphs evidenced activity of peripheral clocks in adults and activity of the central clock in nymphs of T. infestans.es
dc.format.mediumImpreso
dc.language.isoenges
dc.publisherAmerican Society of Tropical Medicine and Hygieneen
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectChagas Diseasees
dc.subjectTriatoma Infestanses
dc.subjectClock gene periodes
dc.titleClock gene period in the Chagas disease vector Triatoma infestans (Hemiptera: Reduviidae)es
dc.typearticlees
dc.description.versioninfo:eu-repo/semantics/publishedVersiones
dc.description.filFil: Stroppa, María Mercedes. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Bioquímica y Biología Molecular; Argentina.es
dc.description.filFil: Stroppa, María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ciencias de la Salud; Argentina.es
dc.description.filFil: García, Beatriz Alicia. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Bioquímica y Biología Molecular; Argentina.es
dc.description.filFil: Giménez, Ignacio. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Cátedra de Bioquímica y Biología Molecular; Argentina.es
dc.journal.cityArlingtones
dc.journal.countryEstados Unidoses
dc.journal.editorialAmerican Society of Tropical Medicine and Hygienees
dc.journal.number2es
dc.journal.pagination468-474es
dc.journal.referatoCon referato
dc.journal.titleAmerican Journal of Tropical Medicine and Hygienees
dc.journal.volume98es
dc.description.fieldBioquímica y Biología Molecular (ídem 3.1.10)
dc.identifier.eissn1476-1645


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