dc.contributor.author | Graafen, Dirk | |
dc.contributor.author | Neudert, Oliver | |
dc.contributor.author | Buljubasich Gentiletti, Lisandro | |
dc.contributor.author | Franzoni, María Belén | |
dc.contributor.author | Dechent, Jan Falk | |
dc.contributor.author | Münnemann, Kerstin | |
dc.date.accessioned | 2022-06-14T17:06:30Z | |
dc.date.available | 2022-06-14T17:06:30Z | |
dc.date.issued | 2014 | |
dc.identifier.uri | http://hdl.handle.net/11086/26309 | |
dc.description.abstract | Despite their wide applicability in natural sciences, NMR and MRI still suffer from their inherently low sensitivity. This can be overcome by hyperpolarisation techniques, such as parahydrogen-induced polarisation and dynamic nuclear polarisation. Here, we focus on the generation of 1H-hyperpolarised substances with both methods. We especially address the severe lifetime issue of the accomplished 1H hyperpolarisation by demonstrating the production of hyperpolarised liquids in a continuous flow fashion and the storage of hyperpolarisation in slowly relaxing singlet states. Another problem of hyperpolarised proton NMR and MRI is the generation of contrast between a small amount of hyperpolarised molecules and a vast thermal background signal. In this contribution, we show the possibility to use the special signal pattern that is inherent to the hyperpolarisation method to generate excellent MRI contrast which may open up unprecedented opportunities to use the standard MRI nucleus 1H, for example, biomedical applications in future. | es |
dc.format.medium | Impreso | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | * |
dc.rights | restrictedAccess | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.source | ISSN: 0066-4103 | |
dc.source | ISBN: 978-0-12-800184-4 | |
dc.subject | PHIP | en |
dc.subject | DNP | en |
dc.subject | NMR | en |
dc.subject | MRI | en |
dc.subject | Hyperpolarisation | en |
dc.subject | Polarising agents | en |
dc.subject | Signal enhancement | en |
dc.subject | Singlet states | en |
dc.subject | Continuous hyperpolarisation | en |
dc.subject | Magnetic resonance imaging | en |
dc.subject | Nuclear magnetic resonance | en |
dc.title | 1H NMR Spectroscopy and MR Imaging with hyperpolarised substances | en |
dc.type | bookPart | en |
dc.description.fil | Fil: Graafen, Dirk. Max Planck Institute for Polymer Research; Germany. | es |
dc.description.fil | Fil: Ebert, Sandro. Max Planck Institute for Polymer Research; Germany. | es |
dc.description.fil | Fil: Ebert, Sandro. Johannes Gutenberg University Medical Center. Department of Radiology; Germany. | es |
dc.description.fil | Fil: Buljubasich Gentiletti, Lisandro. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. | es |
dc.description.fil | Fil: Buljubasich Gentiletti, Lisandro. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. | es |
dc.description.fil | Fil: Buljubasich Gentiletti, Lisandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina. | es |
dc.description.fil | Fil: Franzoni, María Belén. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina. | es |
dc.description.fil | Fil: Franzoni, María Belén. Universidad Nacional de Córdoba. Instituto de Física Enrique Gaviola; Argentina. | es |
dc.description.fil | Fil: Franzoni, María Belén. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Física Enrique Gaviola; Argentina. | es |
dc.description.fil | Fil: Dechent, Jan Falk. Max Planck Institute for Polymer Research; Germany. | es |
dc.description.fil | Fil: Münnemann, Kerstin. Max Planck Institute for Polymer Research; Germany. | es |
dc.journal.referato | Con referato | |
dc.description.field | Física Atómica, Molecular y Química (física de átomos y moléculas incluyendo colisión, interacción con radiación, resonancia magnética, Moessbauer Efecto.) | |
dc.book.pages | 167-215. | en |
dc.book.volume | 82 | en |
dc.book.title | Annual Reports on NMR Spectroscopy | en |
dc.identifier.url | http://dx.doi.org/10.1016/B978-0-12-800184-4.00004-7 | |
dc.identifier.doi | http://dx.doi.org/10.1016/B978-0-12-800184-4.00004-7 | |