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Expression of key steroidogenic enzymes in developing brain: hormonal compensation of sex chromosomes-induced sex differences

dc.contributor.authorCisternas, Carla Daniela
dc.contributor.authorTomé, Karina
dc.contributor.authorCambiasso, María Julia
dc.date.accessioned2021-12-09T16:17:58Z
dc.date.available2021-12-09T16:17:58Z
dc.date.issued2014
dc.identifier.urihttp://hdl.handle.net/11086/21946
dc.description.abstractDeveloping brain of mammals is organized by gonadal steroids during the critical period of sexual differentiation (E18-PN10). The regulatory role of neurosteroids in the early brain is unclear. It is known that 17-β-estradiol (E2) is produced within the brain itself primarily due to local aromatization of gonadal testosterone and also due to de novo synthesis from cholesterol. Little is known about the circulating and local levels of steroids in the embryonic brain. Thus, the use of animal models that dissociate the effect of gonadal sex from sex chromosomes heritage facilitates the study of organizational actions of gonadal steroids and neurosteroids in each sex.es
dc.description.urihttp://www.saneurociencias.org.ar/congreso-2014/
dc.format.mediumElectrónico y/o Digital
dc.language.isoenges
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by-nc-sa/4.0/*
dc.subjectAromatasaes
dc.subjectCerebroes
dc.subjectCromosomases
dc.titleExpression of key steroidogenic enzymes in developing brain: hormonal compensation of sex chromosomes-induced sex differenceses
dc.typeconferenceObjectes
dc.description.filFil: Cisternas, Carla Daniela. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra Introducción a la Química y Física Biológicas A; Argentina.es
dc.description.filFil: Cisternas, Carla Daniela. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.es
dc.description.filFil: Tomé, Karina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentinaes
dc.description.filFil: Cambiasso, María Julia. Universidad Nacional de Córdoba. Facultad de Odontología. Cátedra de Biología Celular B; Argentina.es
dc.description.filFil: Cambiasso, María Julia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentina.es
dc.description.fieldBioquímica y Biología Molecular (ídem 3.1.10)
dc.conference.cityCiudad Autónoma de Buenos Aires
dc.conference.countryArgentina
dc.conference.editorialSociedad Argentina de Investigación en Neurociencias
dc.conference.eventXXIV Reunión Anual de la Sociedad Argentina de Investigación en Neurociencias
dc.conference.eventcityHuerta Grande Cordoba
dc.conference.eventcountryArgentina
dc.conference.eventdate2014-10
dc.conference.journalActas del congreso XXIV Reunión Anual de la Sociedad Argentina de Investigación en Neurociencias
dc.conference.publicationLibro
dc.conference.workResumen
dc.conference.typeCongreso


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