Facultad de Ciencias Químicas: Recent submissions
Now showing items 1-20 of 747
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Monitoreo de microplásticos en el Área Marina Protegida Namuncurá - Banco Burdwood, y el talud circundante
(Editorial Parques Nacionales, 2024)Los ecosistemas marinos se encuentran afectados por grandes cantidades de residuos plásticos. A través de las desembocaduras de los ríos, corrientes oceánicas, vientos y deriva, los desechos plásticos pueden ser transportados ... -
Exploring Scoring Function Space: Developing Computational Models for Drug Discovery
(2024-05-01)Background: The idea of scoring function space established a systems-level approach to address the development of models to predict the affinity of drug molecules by those interested in drug discovery. Objective: Our goal ... -
Hexacoordinated tin complexes catalyse imine hydrogenation with H2
(2024-02-16)Frustrated Lewis pair (FLP) hydrogenation catalysts predominantly use alkyl- and aryl-substituted Lewis acids (LA) that offer a limited number of combinations of substituents, limiting our ability to tune their properties ... -
Geometry-induced Bloch point domain wall in Permalloy conical frustum nanowires for advanced spintronics applications
(2024-04-29)In this study, we investigate the pseudo-static magnetic properties of Permalloy conical frustum nanowires using micromagnetic simulations. We thoroughly examine how both the major and minor radii influence the magnetic ... -
A multicriteria GIS-based approach for mapping biomass agricultural residues availability for biopower plants
(2024-01-24)The development of accurate bioenergetic models, that simulate scenarios for decision making and policy planning contributions, has become a necessity in the actual climate crisis context. The objective of this work is to ... -
Palladium nanoparticles for the synthesis of phenanthridinones and benzo[c]chromenes via C–H activation reaction
(2024-06-11)In the present work, derivatives of phenanthridine-6(5H)-ones and benzo[c]chromenes were efficiently prepared through an intramolecular C–H bond functionalization reaction catalyzed by photochemically synthesized Pd-PVP ... -
Rational Design of 2D Supramolecular Networks Switchable by External Electric Fields
(2024-01-23)The reversible formation of hydrogen bonds is a ubiquitous mechanism for controlling molecular assembly in biological systems. However, achieving predictable reversibility in artificial two-dimensional (2D) materials remains ... -
Bay-Substitution of Perylene Bisimides with Bidentate Nucleophiles: The Case of Aryloxide Anions
(2024-01-25)In this study, we delve into the regioselectivity of nucleophilic reactions involving brominated perylene bisimides (PBIs) and various bidentate aryloxide anions, previously associated with an SRN1 mechanism. We present ... -
Arabidopsis DNA glycosylase MBD4L improves recovery of aged seeds
(Society for Experimental Biology, 2024-06-04)DNA glycosylases initiate the base excision repair (BER) pathway by catalyzing the removal of damaged or mismatched bases from DNA. The Arabidopsis DNA glycosylase methyl-CpG-binding domain protein 4 like (MBD4L) is a ... -
Diseño y desarrollo de nanopartículas proteicas para la administración de melatonina como agente neuroprotector en el tratamiento de patologías neurodegenerativas oculares
(2024-07-01)El presente trabajo de Tesis Doctoral aborda el desarrollo de nuevas plataformas nanotecnológicas de liberación de fármacos, para la optimización de la farmacoterapia de patologías neurodegenerativas oculares como el ... -
Intervención de un farmacéutico especialista en el servicio de hemodinamia
(2024-07-01)En la actualidad, la cantidad de procedimientos que se llevan a cabo en el servicio de hemodinamia aumentan considerablemente. Una explicación radica en que se comprobó que un número mayor de intervención quirúrgicas de ... -
Understanding the effects of omega-3 fatty acid supplementation on the physical properties of brain lipid membranes
(2024-07-19)A deficiency in omega-3 fatty acids (ω3 FAs) in the brain has been correlated with cognitive impairment, learning deficiencies, and behavioral changes. In this study, we provided ω3 FAs as a supplement to spontaneously ... -
Synthesis of Silver Nanostructures on Different Supports: From Nanoparticle Decoration to a Complete Shell Growth
(2024-04-18)In this work, we investigate a complete strategy to obtain supported silver nanostructures (AgNSs) which can be used for different applications such as catalysis, optoelectronics, and biomedical devices. Given the poor ... -
Pharmacological Modulation of the Cytosolic Oscillator Afects Glioblastoma Cell Biology
(2024-06-22)The circadian system is a conserved time-keeping machinery that regulates a wide range of processes such as sleep/wake, feeding/fasting, and activity/rest cycles to coordinate behavior and physiology. Circadian disruption ... -
Efecto del ambiente lipídico en la conformación y orientación de los segmentos transmembrana y citoplasmáticos de la integrina ællbß3
(2024-07-01)Las integrinas son proteínas integrales de membranas. Son grandes receptores de superficie celular heterodiméricos (αβ) que desempeñan un papel clave en la formación de complejos de adhesión a la matriz extracelular y ... -
Desde el timo a la periferia: explorando el origen y rol de células T CD8+ de memoria virtual en modelos murinos y en humanos
(2024-07-01)El timo es un órgano linfático primario (OLP) de gran importancia para el sistema inmune, donde ocurre el desarrollo y la diferenciación de los timocitos que van a constituir distintos linajes de células T, algunas de ellas ... -
The Effects of Chia Defatted Flour as a Nutritional Supplement in C57BL/6 Mice Fed a Low-Quality Diet
(2024-02-23)Today, consumption of diets rich in saturated fat and fructose, associated with a variety of metabolic deregulations, has increased. The aim of this study was to evaluate the effect of dietary supplementation with a residue ... -
Enhancing structural diversity through chemical engineering of Ambrosia tenuifolia extract for novel anti-glioblastoma compounds
(2024-06-20)Natural products are an unsurpassed source of leading structures in drug discovery. The biosynthetic machinery of the producing organism offers an important source for modifying complex natural products, leading to analogs ... -
Ecotoxicological Characterization of Lithium as a “Timebomb” in Aquatic Systems: Tadpoles of the South American Toad Rhinellaarenarum (Hensel, 1867) as Model Organisms
(2024-02-25)The aim of this study was to evaluate the acute lethality and chronic sublethal effects of lithium (Li) on Rhinella arenarum tadpoles as model organisms. First a 96 h toxicity assay was performed by exposing tadpoles to ... -
Magnetic hybrid nanomaterial based on a natural polymer and an amino acid as pH/temperature dual-responsive nanoplatform for the delivery of tamoxifen
(2024-04-12)Magnetic hybrid nanomaterials offer promising properties for the advancement of nanoplatforms in cancer nanomedicine, particularly in drug delivery applications. These nanoplatforms can effectively respond to various stimuli ...