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Neurogenin 3 mediates sex chromosome effects on the generation of sex differences in hypothalamic neuronal development.
(Frontiers in Cellular Neuroscience., 2014)
The organizational action of testosterone during critical periods of development is the cause of numer o ussex differences in the brain. However, sex differences in neuritogenesis have been detectedin primary neuronal ...
Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
(2016)
Estrogens generate a wide diversity of rapid “non-classical” effects which occur in a range from some seconds to few minutes (Arevalo et al., 2012), including the triggering of Ca2+ signals (Wong et al., 2012) and the ...
Sex differences in gene expression of X-linked histone demethylase Kdm6a in embryonic hypothalamic neurons
(2018)
Kdm6a and Kdm5c are histone demethylases that play an important role as epigenetic regulators of gene transcription by removing the di- and tri-methylation of Lys27 or Lys4 on histone H3 (H3K27me2/me3 - H3K4me2/me3). Both ...
Role of sex chromosome complement in the regulation of aromatase expression in developing mice brain
(2016)
During the critical period of sexual differentiation there are sex differences in brain aromatase expression that are time and regionally specific. Some of these sex differences cannot be explained by
organizational — ...
Role of X-linked genes on sex differences in neurogenin 3 expression in developing hypothalamic neurons
(2016)
Our previous findings indicate that sex chromosome complement regulates the generation of sex differences in mouse hypothalamic neuronal development. Higher expression of neurogenin 3 (Ngn3) in XX neurons mediates sex ...