Search
Now showing items 1-9 of 9
Activation of erk1/2 and axogenesis induced by estradiol depend on different calcium pools in male rat hypothalamic neurons in vitro
(2016)
Estrogens generate a wide diversity of rapid “non-classical” effects which occur in a range from some seconds to few minutes (Arevalo et al., 2012), including the triggering of Ca2+ signals (Wong et al., 2012) and the ...
Sex differences in gene expression of X-linked histone demethylase Kdm6a in embryonic hypothalamic neurons
(2018)
Kdm6a and Kdm5c are histone demethylases that play an important role as epigenetic regulators of gene transcription by removing the di- and tri-methylation of Lys27 or Lys4 on histone H3 (H3K27me2/me3 - H3K4me2/me3). Both ...
Expression of key steroidogenic enzymes in developing brain: hormonal compensation of sex chromosomes-induced sex differences
(2014)
Developing brain of mammals is organized by gonadal steroids during the critical period of sexual differentiation (E18-PN10). The regulatory role of neurosteroids in the early brain is unclear. It is known that 17-β-estradiol ...
Sex differences in X-linked gene expression in embryonic hypothalamic neurons
(Sociedad Argentina de Investigación en Neurociencias, 2017)
Although sex hormones are usually considered the main architects of sexual dimorphisms, recent studies have demonstrated that sex chromosomes can also induce sex differences in somatic gene expression in the absence of ...
Sex differences in GABA-mediated calcium influx in hypothalamic neurons
(2018)
GABAA receptor (GABAAR) activation exerts trophic actions in immature neurons through depolarization of resting membrane potential gating the opening of voltage-dependent calcium channels. Previous results from our lab ...
Abolition of the sex difference in Ngn3 by estradiol is depending on sex chromosome complement
(Universidad Nacional de Córdoba, 2014)
A growing body of evidences indicates that some sexually dimorphic traits cannot be solely explained as a result of gonadal steroid action during the critical period of brain masculinization (E18-PN10).
Neurogenin 3 ...
Role of sex chromosome complement in the regulation of aromatase expression in developing mice brain
(2016)
During the critical period of sexual differentiation there are sex differences in brain aromatase expression that are time and regionally specific. Some of these sex differences cannot be explained by
organizational — ...
Sexual dimorphism in renal angiotensin receptors gene expression: sex chromosome complement involvement
(2016)
The process of biological sex differentiation involves genetic and hormonal developmental steps.
Clinical and basic findings indicate that the angiotensinergic system differentially regulates hydroelectrolyte and ...
Role of X-linked genes on sex differences in neurogenin 3 expression in developing hypothalamic neurons
(2016)
Our previous findings indicate that sex chromosome complement regulates the generation of sex differences in mouse hypothalamic neuronal development. Higher expression of neurogenin 3 (Ngn3) in XX neurons mediates sex ...