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dc.contributor.authorKembro, Jackelyn Melissa
dc.contributor.authorCortassa, Sonia
dc.contributor.authorLloyd, David
dc.contributor.authorSollot, Steven
dc.contributor.authorAon, Miguel
dc.date.accessioned2020-11-17T19:20:08Z
dc.date.available2020-11-17T19:20:08Z
dc.date.issued2018-09-26
dc.identifier.citationKembro, Jackelyn Melissa; Cortassa, Sonia; Lloyd, David; Sollott, Steven; Aon, Miguel (2018): Periodic oscillations in mitochondrial function under oxidative stress. SOD2 concentrations of 0.0164 mM. figshare. Dataset. https://doi.org/10.6084/m9.figshare.7117910.v1es
dc.identifier.urihttp://hdl.handle.net/11086/16807
dc.description.abstractNumerical integration of the ME-R model equations was performed with MatCont 2.4 in MATLAB 7.1, until steady-state solutions were obtained (i.e., when the magnitude of each time derivative was -10). Time series with duration of at least 6e6 ms were constructed by numerical integration of model equations. To allow transient states to vanish, the system was computed during a time lapse of 2 e8 ms. All studies were performed using the parameter setting optimized in our previous work (Kembro et al. 2013. Biophys J 104(2):332-343; Kembro et al., 2014. Front Physiol 5:257), with ADPm = 0.01mM, i.e. consistent with energized mitochondria under state 4 respiration. The two .txt file represents the time reference and the time series of variables output of the model, in order from left to right column: 1) Mitochondrial Ca+;2) Mitochondrial ADP; 3) Membrane potential; 4)Mitocondrial NADH; 5) Mitochondrial H+; 6) Mitochondrial Phosfate, Pi; 7) Isocitrate; 8) a-ketoglutarate; 9) Succinyl CoA; 10) Succinate; 11) Fumarate; 12) Malate; 13) Oxaloacetate; 14) NADPH; 15) Mitochondrial superoxide; 16) Extramitochondrial superoxide; 17) Mitochondrial hydrogen peroxide; 18) Extramitochondrial hydrogen peroxide; 19) Mitochondrial GSH; 20) Extramitochondrial GSH; 21)Mitochondrial GSSG; 22) Mitochondrial TrxSH2; 23) ExtramitochondrialTrxSH; 24)Mitochondrial PSSGm; 25) Extramitochondrial PSSG.es
dc.language.isoenges
dc.relationinfo:eu-repo/semantics/altIdentifier/doi/10.6084/m9.figshare.6025748.v1
dc.relationinfo:eu-repo/semantics/reference/hdl/11086/17029
dc.rightsAtribución-NoComercial-CompartirIgual 4.0 Internacional*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectAnimal Physiology - Biophysicses
dc.subjectAnimal Physiology - Systemses
dc.subjectBiophysicses
dc.subjectMitochondriaes
dc.subjectBioenergetics modeles
dc.subjectOxidative stress effectses
dc.subjectOxidative stress enzymeses
dc.subjecthttps://purl.org/becyt/ford/4.3
dc.titlePeriodic oscillations in mitochondrial function under oxidative stress. SOD2 concentrations of 0.0164 mMes
dc.typedataSetes
dc.description.filFil: Kembro, Jackelyn Melissa. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales; Argentina.es
dc.description.filFil: Kembro, Jackelyn Melissa. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina.es
dc.description.filFil: Cortassa, Sonia. National Institutes of Health. NIH · NIA Intramural Research Program; Estados Unidos.es
dc.description.filFil: Lloyd, David. Cardiff University. School of Biosciences 1; Inglaterra.es
dc.description.filFil: Sollot, Steven. Johns Hopkins University. Laboratory of Cardiovascular Science; Estados Unidos.es
dc.description.filFil: Aon, Miguel. Johns Hopkins University. Laboratory of Cardiovascular Science; Estados Unidos.es


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