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Role of ghrelin on nitric oxide secretion and implantation in mice
(2013)
During pregnancy maternal a Ghrelin (Ghr) concentration increases significantly, suggesting an important role of the peptide on the process. The objective of the present study was to evaluate the role of Ghr on implantation ...
Traking a novel human adenovirus in untreated sewages waters of Córdoba City
(2013)
Recent studies highlight the utility of analyzing untreated sewage waters to monitor shedding of viral pathogens and provide genetic information of newly species identified. In recent years, several types of human ...
Persistence of Trypanosoma cruzi in the chronic phase of Chagas disease
(2013)
One of the most important determinants of congestive heart failure and sudden death in Latin America is Chagas disease, provoked by infection with the intracellular protozoan parasiteTrypanosoma cruzi. It affects approximately ...
A novel CLN8 missense mutation underlies variant late infantile neuronal ceroid lipofuscinosis in Latin America
(2013)
Neuronal ceroid lipofuscinosis (NCL), inheritedneurodegenerative diseases of all ages, presents with storage oflipofuscin-like lipopigments in cerebral neurons and peripheraltissues. Mutations in CLN8 gene causing epilepsy ...
Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth
(2018)
The cellular transformation of normal functional cells to neoplastic ones implies alterations in the cellular metabolism and mitochondrial function in order to provide the bioenergetics and growth requirements for tumour ...
A novel CLN8 mutation underlies a late Infantile variant of neuronal ceroid lipofuscinosis in Latin America
(2013)
Introduction: Neuronal ceroid lipofuscinosis (NCL), inherited neurodegenerative diseases of all ages, presents with storage of lipofuscin-like lipopigments in cerebral neurons and peripheral tissues. Mutations in CLN8 ...
The response of prostate smooth muscle cells to testosterone is determined by the subcellular distribution of the androgen receptor
(2018)
Androgen signaling in prostate smooth muscle cells (pSMCs) is critical for the maintenance of prostate homeostasis, the alterations of which are a central aspect in the development of pathological conditions. Testosterone ...
Population-Based Study of New Mutations Causing Sandhoff Disease in Argentina
(Sociedad Americana de errores innatos del metabolismo y pesquisa neonatal, 2013)
Sandhoff Disease (SD) is a lysosomal storage disorder caused by mutations in the HEXB gene. A high incidence
of SD has been described in an Argentine region called ‘‘Valle de Traslasierra.’’ Mutations c.445þ1G>A and ...
Resultados preliminares: dietas con diferente relación n6/n3 pueden modificar el éxito reproductivo, la gestación y el desarrollo de placentas y embriones de ratónPreliminary results: diets with different n6/n3 ratios may modify reproductive success, gestation, placental and embryonic development of mouse
(Universidad Nacional de Córdoba. Facultad de Ciencias Médicas, 2013)
Omega 3 essential fatty acids (n3) are involved in reproductive physiology and early development of mammals. Objective: to assess reproductive success (RS), evolution of gestation, and fetal and placental development of ...
Effects of ω-3 PUFA-enriched diet on growth parameters in a syngenic murine model of breast adenocarcinoma: a possible role for estrogen receptor alpha
(2013)
Background: Breast cancer (BC) is the most common tumour among women and 75% of BC are estrogen receptor
(ER)dependent. In particular, ERα promotes tumour growth, while ERβ has an anti-proliferative effect [1].
Epidemiological ...