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Sex differences in active DNA demethylation machinery during the critical period of brain masculinization
(2022)
In mammals, perinatal peaks in gonadal testosterone organize a sex-typical neural circuitry during sensitive periods of development and a growing body of evidence suggest that epigenetic mechanisms are implicated. Some of ...
Histone deacetylase gene expression is regulated by sex chromosome complement in the amygdala of the developing mouse brain
(2020)
Sexual differentiation of the rodent brain depends mainly on the action of androgens secreted by the fetal testis during the perinatal critical period (E17-P10). Recently, the role of genetic factors derived from sex ...
Expression of key steroidogenic enzymes in developing brain: hormonal compensation of sex chromosomes-induced sex differences
(2014)
Developing brain of mammals is organized by gonadal steroids during the critical period of sexual differentiation (E18-PN10). The regulatory role of neurosteroids in the early brain is unclear. It is known that 17-β-estradiol ...
Sex differences in X-linked gene expression in embryonic hypothalamic neurons
(Sociedad Argentina de Investigación en Neurociencias, 2017)
Although sex hormones are usually considered the main architects of sexual dimorphisms, recent studies have demonstrated that sex chromosomes can also induce sex differences in somatic gene expression in the absence of ...
Abolition of the sex difference in Ngn3 by estradiol is depending on sex chromosome complement
(Universidad Nacional de Córdoba, 2014)
A growing body of evidences indicates that some sexually dimorphic traits cannot be solely explained as a result of gonadal steroid action during the critical period of brain masculinization (E18-PN10).
Neurogenin 3 ...
Role of sex chromosome complement in the regulation of aromatase expression in developing mice brain
(2016)
During the critical period of sexual differentiation there are sex differences in brain aromatase expression that are time and regionally specific. Some of these sex differences cannot be explained by
organizational — ...
Early sex differences in histone methyl transferase EZH2 expression in developing hypothalamus of the mouse brain
(2022)
In mammals, the primary agents causing phenotypic sex differences are encoded by sex chromosomes. Many of X-and Y-linked genes are epigenetic modifiers and pivotal evidence in past 7 years implicates epigenetic mechanisms ...
Role of X-linked genes on sex differences in neurogenin 3 expression in developing hypothalamic neurons
(2016)
Our previous findings indicate that sex chromosome complement regulates the generation of sex differences in mouse hypothalamic neuronal development. Higher expression of neurogenin 3 (Ngn3) in XX neurons mediates sex ...